GROUP MEMBERS

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JAMES BOURNE

Professor and Group Leader
NHMRC Senior Research Fellow

James completed his undergraduate training in Biochemistry (Hons) at the Imperial College, London and carried on to undertake a PhD in the field of Neuropharmacology with the Ministry of Defence and Kings College, London. He then relocated to Australia to undertake a Postdoctoral position at the Vision, Touch and Hearing Research Centre at UQ, later moving to Monash University where in 2007 he started up his own research group. James holds an NHMRC Senior Research Fellowship, is a member of the NHMRC Research Committee and has a strong track record in the field of neural development and regeneration of the visual system. He heads the Bourne group, with his skills and expertise in nonhuman primate research enabling the group to undertake cross-disciplinary research collaborations which form an important component of translational research to humans.

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JIHANE HOMMAN-LUDIYE

Post Doctoral Fellow

Following her undergraduate training in Cell Biology and Physiology at the University Denis Diderot (Paris VII, France), Jihane completed a Master in Neuropharmacology at the Ecole Normale Superieure (Paris, France) and obtained a doctoral scholarship from the French Ministry of Research and Higher Education to investigate the role of the vascular endothelial growth factor C (VEGF-C) on the development of discrete population of neural progenitors in the developing brain. After gaining her PhD from the University Pierre and Marie Curie (Paris VI, France), she joined A/Prof Bourne’s group at Monash University (Melbourne, Australia) in 2008 to investigate the molecular mechanisms regulating the development of the primate neocortex and thalamus.

She has adapted molecular and tissue culture techniques acquired during her doctoral training to the complex primate brain in order to elucidate the sequence of event underlying the specification of brain structures exclusive to the primate.

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Iñaki Carril Mundiñano

Post Doctoral Fellow

Inaki completed his PhD at the University of the Basque Country (Leioa, Spain) studying sensory crossmodal plasticity early blindness. He undertook his first postdoc in the Laboratory of Regenerative Therapy Neuroscience, (CIMA/UNAV, Pamplona, Spain) where his research focused on the development of a new genetic animal model of Parkinson’s disease in the macaque monkey; and on the olfactory neuropathology of patients with different neurodegenerative disorders.

In 2013 Iñaki joined the Bourne Lab to study the involvement of the pulvinar nucleus in cortical development and behaviour. He uses several approaches including lesioning, neural tracing, immunohistochemistry, neuroimaging and behavioural studies. Inaki has also developed new MRI-guided neurosurgical techniques which has led to international collaborations and publications on the technique.

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LEON TEO

Post Doctoral Fellow

Leon' completed his PhD with the Bourne Group in 2015, establishing a clinically representable model of ischemic stroke in the nonhuman primate. Leon's PhD work focused on the cellular and molecular changes following brain injuries and how they differ between the infant and adult brains to better understand the capacity for endogenous repair after injuries.

Now as a research fellow, Leon has developed a novel therapeutic strategy for the treatment of stroke and is leading a pre-clinical trial to test its efficacy for functional improvements after stroke. If successful, this strategy will significantly extend the therapeutic window from hours into days post-stroke, which will be of immense benefit to stroke patients worldwide.

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WILLIAM KWAN

Lab Manager and Research Assistant

William joined the Bourne Laboratory in 2009 and assists the group's research as a research assistant. As well as general lab duties William also assists with many of the surgical experiments in particular the MRI guided subcortical tracing the lab routinely employs (Mundinano et al 2016. Nat. Protoc.) Currently William is studying the role of Area MT and its role in early life development in the visual system by using neural tracing and visual behaviour experiments.

When he is not researching visual neuroscience, William enjoys beekeeping and being in the outdoors.

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ANTHONY BOGHDADI

PhD Student

Anthony completed his Bachelor of Science in 2012 at Monash University, Clayton, majoring in Anatomy/Developmental Biology and Immunology/Human Pathology. In his final year he undertook a mini-research project in the Bourne Lab, subsequently undertaking a Summer Project. These experiences peaked his interest in Neuroscience, in particular towards a group of myelin-associated proteins and how they may have key roles in regulating plasticity and repair inhibition following CNS injury. Staying in the lab for Honours, he started characterising these proteins in the neonate and adult nonhuman primate neocortex. He is currently undertaking his PhD investigating these myelin proteins more in-depth, specifically how cells expressing them respond in the acute stages following neocortical injury and what implications this may have in terms of their roles in neurorepair versus neurodegeneration.

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DYLAN FOX

PhD Student

Dylan completed his Bachelor of Behavioural Neuroscience at Monash University in 2014. He later joined the Bourne group in 2015 for his Honours year where his project aimed to develop protocols for the voluntary training and assessment of the awake/conscious marmoset in their visually guided actions. He continued with the group as a PhD student, applying his behavioural procedures complemented with connectional and anatomical techniques to investigate the function of the inferior pulvinar nucleus in the early development of visually guided actions such as reaching to grasp for target objects. 

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KEVIN Chang

PhD Student

Kevin completed his Bachelor of Science (Neuroscience Major) at Melbourne University in 2016 and now undertaking a master degree in the Bourne lab. He is particularly interested in behavioural changes following early life brain lesions. His current research focuses on area MT and how this area plays a role during development.

 
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JACK SCOTT

PhD Student

Jack completed a Bachelor of Science at the University of Melbourne in 2014, a Master of Biomedical and Health Science at Monash University in 2018, and is currently undertaking a PhD with the Bourne Group. He has a keen interest in the neural pathways underlying cognition and affect, and how the function of these pathways can be measured through behaviour. His research focuses on the developmental role of the medial pulvinar, and how its impairment may lead to changes in behaviour that are typically associated with schizophrenia. Jack is also interested in innovations in automated behavioural analysis, and how these new technologies may be applied to a variety of research questions.

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Kieren Pinto

BMS3990 Student

Kieren is undertaking a double degree Bachelor of Biomedical Sciences/Engineering at Monash University. His time in the Bourne Lab started in early 2018, when he commenced as a UROP (Undergraduate Research Opportunity) scholar. During this time, Kieren assisted with developing behavioural research techniques alongside Dylan Fox, to understand the thalamic substrate responsible for blindsight. He was also seminal in the development of an automated neuropsychological test system, to assess the cognitive performance of non-human primates in various experimental scenarios. At the conclusion of this program, Kieren has continued his appointment in the Bourne Lab as a BMS3990 student in 2019, and is now working closely with Jack Scott and Inaki Carril Mundinano to understand the role of the medial pulvinar in schizophrenia and the underlying changes in structure and connectivity that occur.

 

Darren RAJIT

UROP Student

bio to come…

 
 

LAB ALUMNI

 

Post-doctoral Research Fellows
Lievan Huang (2015-16)
Claire Warner (2014-15)

Research Assistants
Mitchell DeSouza (2015-17)

Research Technicians
Bruno Mendivez (2017-18)
Felix Sng (2017-18)

Honours Students
Adrian Yip (2018)
Jason Ha (2017)
Nicholas Renton (2016)
Lewis Fry (2015)
Phil Bennet-Owen (2014)
Jing Wang (2014)
Skye Kinder (2011)
Dania Foo (2009)
Yi Sia (2007)